This workshop provides participants with a critical examination of how Artificial Intelligence (AI) is transforming the landscape of cancer clinical trials. Focused on the applications of AI in clinical trial design, patient recruitment, data analysis, and outcome prediction, the workshop aims to enhance the efficiency, accuracy, and success of clinical trials in oncology. Participants, including clinical researchers, healthcare IT specialists, and policymakers, are capacitated with the tools and knowledge necessary to utilise AI technologies effectively, to improve patient outcomes and streamline research efforts. Through hands-on activities and selected case studies, participants will learn to apply advanced predictive analytics techniques in clinical trials’ context. Legal, Social, Ethical, Professional and regulatory considerations surrounding AI utilisation are critically discussed with particular reflections on data privacy, transparency, and compliance. Through collaborative learning and practical applications, this workshop seeks to facilitate the development of more effective, patient-cantered, and data-driven clinical trials to advance cancer care comprehensively.